Yeah, it's tough when you don't have a lot of time. We had only four nights so spent the entire time in Healdsburg exploring it and Sonoma. Still need another week there, then a few in Napa...Santa Barbara county... yeah. frankly, this is going to be a food and bed vacation. once a year we get to leave the kids for a few days. last year it was new orleans. there is a lot to do/see/eat in san fran, I've been there a dozen or more times, my wife hasn't ever. so it will be hard to choose.