Quote:
Originally Posted by
lee_44106 
Not only are Noo Yorkers annoying for thinking that NYC is everything, but now we are debating a friggin street name.
Get over yourself, you are not the center of the universe.
Oh come on Lee - how about a New Year's resolution to stop hating on and obsessing about NYC?

There is rarely a question or topic about the city where you don't pop up your head to scream "FU New York!", even your location in your profile obsesses about NYC... Where is the trauma coming from? do you want to talk about it? We're good listeners.
Here's to start the year:
http://nymag.com/news/articles/reasonstoloveny/2008/ 
To answer the OP: 6th Av of course. Half of the cabbies wouldn't even know what Ave of the Americas is.
Also, does anyone have a good answer as to why Houston Street is pronounced differently from Houston, TX ? My brother asked my last week and I had no idea.
EDIT: fuggedaboutit, found the answer in wikipedia
Quote:
The street name Houston confuses many people from outside of New York (invariably becoming one of the easiest signs of spotting tourists) because the letters "ou" are pronounced as in the word house (pronounced /ˈhaʊstən/), whereas the same letters in the name of the city of Houston, Texas are pronounced like the "u" in huge (pronounced /ˈhjuːstən/ or /ˈjuːstən/, "HYOO-stin"). This is because Houston Street was named for William Houstoun (note that the spelling is different), long before the fame of Sam Houston, for whom the city in Texas is named. Some people mistakenly believe that the pronunciation was popularized by the accents of local Jewish immigrants.