I haven't watched it for a long time, but my favorite episode is where the entire family gets addicted to cigarettes.
HANK: For God's sake, Bobby, what nationality are you?
BOBBY: American.
HANK: Then why are you holding your cigarette like some kind of European Nazi in a movie?
BOBBY: Why does it matter? I thought smoking was bad.
HANK: That's not the right sort of attitude for you to have. Whatever you do, you should do right, even if it's something wrong.
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BOBBY: Hey, all right! You guys smoke too?
HANK: What we do is not the point. I told you not to smoke. Do I have to take you out back with another carton of cigarettes?
BOBBY: I think you do.
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LUANNE: I cannot believe you're all smoking! Don't you know more people die of smoking than die of... war... in Vietnam... every day?
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INSTRUCTOR: How long have you been addicted to cigarettes?
BOBBY: Since my dad let me smoke a whole carton.
HANK: Now wait a minute, I didn't let him, I made him! It was a punishment!
BILL: Can I get a new buddy?
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BOBBY: Why does my potato have skin on it? I hate skin!
PEGGY: I will not sit here and listen to you criticize my work! What, do you think the potatoes just fly into the bowl and mash themselves?
LUANNE: I know y'all don't mean none of those harsh words. It's just the nicotine withdrawal.
HANK: Why is she still talking?