Kill 2 birds- take it to the cleaners. If it's 2 separate ties, if you must iron a tie you can either hang it and steam it with your iron to accelerate the natural process of wrinkle releasing while a garment is hanging, or for a really bad wrinkle you might use an ironing cloth and steam it a touch through the cloth. Don't use any pressure and contact the iron cloth as little as possible, just light bumps through the cloth and a little touch of steam. For a stained tie- cleaners. If you don't have a good cleaner and this is your favorite tie, look into http://tiecrafters.com/. Never used myself, but it might be an option.
I don't know if this is the best way- but I've done it and never had any problems.