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do you smoke weed? - Page 3

post #31 of 130
Quote:
Originally Posted by Tarmac View Post
weed vs alcohol, both have their advantages and disadvantages. right now, the biggest disadvantage for weed is that it is illegal to even possess.
Actually, the biggest disadvantage of weed is it's side effects. Do you have any idea what THC does in your brain? Check this out. The THC acts as a transmitter for Satan and Satan's helpers. See what happens is, when you smoke marijuana, it's like opening up a portal to the devil. Only the portal is in your brain. That means that Satan himself has direct access to your brain and your SOUL. Would you want the devil to have direct access to your frikken soul? The side effects are equally devastating. You might find your mouth getting dry. Scary huh? Wait, there's more. You might even get really hungry and even crave junk food. Yeah. Really. I'm not kidding. That's the work of the devil. God forbid you're with a woman while smoking it. You might even get the urge to fornicate! Fornication is a sinful act and the devil makes you do it! Next thing you know you're listening to Snoop Dogg!
post #32 of 130
i dont have any problem with people who smoke weed. pretty much every one of my friends does it. its the people who make a big deal about it that annoy me.
post #33 of 130
I watch Weeds
post #34 of 130
You are supposed to smoke it?
post #35 of 130
Quote:
Originally Posted by antirabbit View Post
Do you have any idea what THC does in your brain? Do you know where your brain is?

Actually, it does very little to your brain. I do know that alcohol kills exponentially more people than marijuana, and is far more damaging to your body. Talk about being a moron.
post #36 of 130
Quote:
Originally Posted by suited View Post
Actually, it does very little to your brain. I do know that alcohol kills exponentially more people than marijuana, and is far more damaging to your body. Talk about being a moron.

+1.
post #37 of 130
after today's market news, i wish i did...

-Jeff
post #38 of 130
The rule of Weed Club is, you don't talk about Weed Club.
post #39 of 130
Quote:
Originally Posted by Mr T View Post
You are supposed to smoke it?

If you are a smoker you tend to lose that intimate, spirtual connection with the weed a good high can deliver. Try suppository form.
post #40 of 130
i don't do it anymore. i've seen it help some people. i've seen it hurt some people. the thing that frustrates me is that the people it's hurting are adamant that it's helping them in some manner or not doing anything to them at all. i guess it really just depends on the person.
post #41 of 130
Quote:
Originally Posted by Piobaire View Post
The rule of Weed Club is, you don't talk about Weed Club.
Someone broke a cardinal rule.
post #42 of 130
Thread Starter 
i feel sorry for the idiots who think smoking weed is more harmful than drinking alcohol. while smoking anything cant be too good for your lungs you could vaporize weed which will decrease any harmful effects that weed can do to your lungs. also please find me a study from a valid source that PROVES weed can kill braincells, causes cancer, kills people, and anything else your 5th grade teacher told you. you people are very ignorant and are living in the reefer madness days.
post #43 of 130
you are stupid^i agree some people go overboard with the weed being bad etc, but it most definately kills brain cells and can cause cancer. dont be a dumbass! dumbass!
post #44 of 130
Quote:
Originally Posted by suited View Post
Actually, it does very little to your brain. I do know that alcohol kills exponentially more people than marijuana, and is far more damaging to your body. Talk about being a moron.

Ok, I bow down to your expertise in Neuroscience, I am a moron.

(hint, it has to do with the soluability of THC in water vs. the soluability of THC in lipids you dumb ass...)

In humans, psychoactive cannabinoids produce euphoria, enhancement of sensory perception, tachycardia, antinociception, difficulties in concentration and impairment of memory. The cognitive deficiencies seem to persist after withdrawal. The toxicity of marijuana has been underestimated for a long time, since recent findings revealed Δ9-THC-induced cell death with shrinkage of neurons and DNA fragmentation in the hippocampus.

The acute effects of cannabinoids as well as the development of tolerance are mediated by G protein-coupled cannabinoid receptors. The CB1 receptor and its splice variant CB1A, are found predominantly in the brain with highest densitities in the hippocampus, cerebellum and striatum.

The CB2 receptor is found predominantly in the spleen and in haemopoietic cells and has only 44% overall nucleotide sequence identity with the CB1 receptor. The existence of this receptor provided the molecular basis for the immunosuppressive actions of marijuana. The CB1 receptor mediates inhibition of adenylate cyclase, inhibition of N- and P/Q-type calcium channels, stimulation of potassium channels, and activation of mitogen-activated protein kinase. The CB2 receptor mediates inhibition of adenylate cyclase and activation of mitogen-activated protein kinase.

The discovery of endogenous cannabinoid receptor ligands, anandamide (N-arachidonylethanolamine) and 2-arachidonylglycerol made the notion of a central cannabinoid neuromodulatory system plausible. Anandamide is released from neurons upon depolarization through a mechanism that requires calcium-dependent cleavage from a phospholipid precursor in neuronal membranes. The release of anandamide is followed by rapid uptake into the plasma and hydrolysis by fatty-acid amidohydrolase.

The psychoactive cannabinoids increase the activity of dopaminergic neurons in the ventral tegmental area-mesolimbic pathway. Since these dopaminergic circuits are known to play a pivotal role in mediating the reinforcing (rewarding) effects of the most drugs of abuse, the enhanced dopaminergic drive elicited by the cannabinoids is thought to underlie the reinforcing and abuse properties of marijuana.

Thus, cannabinoids share a final common neuronal action with other major drugs of abuse such as morphine, ethanol and nicotine in producing facilitation of the mesolimibic dopamine system.

Sounds great...huh?
post #45 of 130
Thread Starter 
Quote:
Originally Posted by antirabbit View Post
Ok, I bow down to your expertise in Neuroscience, I am a moron.

(hint, it has to do with the soluability of THC in water vs. the soluability of THC in lipids you dumb ass...)

In humans, psychoactive cannabinoids produce euphoria, enhancement of sensory perception, tachycardia, antinociception, difficulties in concentration and impairment of memory. The cognitive deficiencies seem to persist after withdrawal. The toxicity of marijuana has been underestimated for a long time, since recent findings revealed Δ9-THC-induced cell death with shrinkage of neurons and DNA fragmentation in the hippocampus.

The acute effects of cannabinoids as well as the development of tolerance are mediated by G protein-coupled cannabinoid receptors. The CB1 receptor and its splice variant CB1A, are found predominantly in the brain with highest densitities in the hippocampus, cerebellum and striatum.

The CB2 receptor is found predominantly in the spleen and in haemopoietic cells and has only 44% overall nucleotide sequence identity with the CB1 receptor. The existence of this receptor provided the molecular basis for the immunosuppressive actions of marijuana. The CB1 receptor mediates inhibition of adenylate cyclase, inhibition of N- and P/Q-type calcium channels, stimulation of potassium channels, and activation of mitogen-activated protein kinase. The CB2 receptor mediates inhibition of adenylate cyclase and activation of mitogen-activated protein kinase.

The discovery of endogenous cannabinoid receptor ligands, anandamide (N-arachidonylethanolamine) and 2-arachidonylglycerol made the notion of a central cannabinoid neuromodulatory system plausible. Anandamide is released from neurons upon depolarization through a mechanism that requires calcium-dependent cleavage from a phospholipid precursor in neuronal membranes. The release of anandamide is followed by rapid uptake into the plasma and hydrolysis by fatty-acid amidohydrolase.

The psychoactive cannabinoids increase the activity of dopaminergic neurons in the ventral tegmental area-mesolimbic pathway. Since these dopaminergic circuits are known to play a pivotal role in mediating the reinforcing (rewarding) effects of the most drugs of abuse, the enhanced dopaminergic drive elicited by the cannabinoids is thought to underlie the reinforcing and abuse properties of marijuana.

Thus, cannabinoids share a final common neuronal action with other major drugs of abuse such as morphine, ethanol and nicotine in producing facilitation of the mesolimibic dopamine system.

Sounds great...huh?
um that means nothing without a good source and the guy who said it causes cancer and kills braincells find a study thats from a good source that says exactly that. they dont even say that bs on the www.abovetheinfluence.com website anymore lmao
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