I really like the look of whole-cut Oxford shoes. What are the pros and cons of whole-cuts, in terms of comfort and durability? Do they have a tendency to get creased up easily?
Wholecuts shouldn't be any more or less comfortable or durable than other styles of shoes, all other things being equal. They're also not more or less likely to get creased up easily, although creases that do develop are more apparent because there is no toe cap or wing cap to camouflage them.
Who makes top quality whole-cuts at relatively good value? (I read that Edward Green offers one of the highest quality to price ratio for shoes.)
Well, EG certainly makes some of the highest-quality RTW shoes available, but I don't know whether their QPR is that great -- they're very expensive shoes at retail. Most of the English makers have a wholecut model. C&J's Weymouth has quite a reputation on this board, and deservedly so:
Many of the Italian manufacturers also have a model. Here's a Gravati that I like: