Pick a drink and stick with it. If you haven't drank before, you'll have a temptation to try a lot of different things, and that will make you throw up. Drinking will also lower your intelligence against mixing different drinks, so make sure that you stick with having only, say, beer. Especially if you are going to an Irish pub! Try different beers, but don't do a beer, tequila and then Baileys on the rocks. Drink a bottle of Gatorade, or better, Vitamin Water (make sure it has B vitamins) before you start drinking and again when you are going to go to bed. Enjoy finding out what you've been missing : )