Bespoke is the highest, most work intensive type of tailoring and shoemaking, to the best of my knowledge. It involves several fittings and results in new patterns being designed for your body (when speaking of suits). To answer your broader question, MY own answer would be yes. Many people, on the contrary, can't tell the difference between a Men's Wearhouse (is it Ware, or Wear anyway?) and an Attolini. I would attribute this mainly to the lack of interest on the subject. Someone with even limited knowledge in the sartorial arts would still recognize a Kiton suit as being an amazing piece. I prefer designer suits, myself. However, any skilled tailor, in Hong Kong or otherwise will give you a better fit through MTM than any ready-to-wear designer (unless you just happen to fit the exact body shape that the designer-wear was made for - highly unlikely). In short, I think after you have developed a taste and start to catch onto details that seperate the good from the bad, you will undoubtedly have an answer to your own question.