Hello Bexcellence.
Wise choice in considering buying GUCCI loafers/oxfords. If you do end up purchasing a pair it will be a decision you will not regret - trust me.
I'm a GUCCI fanatic and have an extensive collection, primarily in shoes. Due to the many shoe options I have, all my shoes are in great shape and have held up great over the years. Consider shoe buying as an investment. My motto is "I'm too poor to buy cheap shoes" so every time I purchase a pair of GUCCI I make sure to also purchase cedar shoe trees. It's a must! In fact, I have some on now.
With that being said, your shoe sizing will vary in GUCCI. Since you wear a 10D in all other shoes you want to make sure that you find size 10D in GUCCI or even size 9G in GUCCI. Any time you see the letter G behind a number it means the size will bump up 1 whole size.
Also, I highly recommend you get to know your European shoe size. This will come in very handy, especially when you want to purchase other high end shoes.