If you had to ask...don't. People who wear bow ties want to wear bow ties. They really enjoy wearing them as it shows their individuality or appreciation for something a little different. Some wear bow ties for practical reasons e.g. Doctors, waiters.
If you think you may feel awkward wearing a bow tie or self conscious because you don't wear one very often, then stick to a tie. Why let an article of clothing distract you from enjoying yourself.
However, if you are wearing a Dinner Jacket/Tux, I would recommend wearing a bow tie.