I guess it'd be the diabetes, but I don't think about it much anymore. Just part of life. Every once and a while I realize how shitty it all is, but I don't know anything else so it barely bothers me most of the time.
Other than that, I've about pushed myself to the limits of my abilities professionally and it requires a lot of self-motivation to be good. I'm not great at pushing myself super hard without some structure, but that's rarely found where I'm at. Lots of paths are opening up in the near future so I think I can deal with it, but something's gotta change long-term.