Right now I am using (sorry if I get the names wrong):
main attack: guided shot with the split arrow runey
right click: rapid fire with rune that decreases cost and maybe adds fire damage?
slot 4 and extra mouse button: multishot with cost decrease rune
1: caltrops with 2 second of total freeze rune
2: vault with shoot as you leap rune
3: throwing knives in a circle or something else depending on expected situation (and this is linked to an extra mouse button too)
passives: one that restores hatred with health globes and the one that increases damage 20% when no enemies are within 10 yards.
usually drop some caltrops and vault away from enemies to keep my damage bonus. Then if it is a really big crowd I will drop multishots, otherwise I will rapid fire through them one by one. If stuff gets low, I can vault back and forth through the crowd of enemies and pick up health globes which gives me back my powers (even with the reduced cost rune, multishot drains hatred really fast)