I love Casamento's for oysters/oyster loaf. Liuzza's By the track for breathtaking beef po-boy. Central Grocery is the only muffaletta I've had and is the famous one. Other favorite po-boy shops are Domalise's, Parkway, Parasol, Verti Marte, etc. There are a ton of boil shops around town where you can get crawfish and crabs, etc. I don't know that one is better than another, although the traditional seafood part of town is Bucktown, so if you want the best, I'd suspect it would be in that area. Sidmars and Deanies are both solid, but I've never been during crawfish season and don't know if they do crawfish. Call ahead. I don't much care - I usually just takeout a bunch of food from one of the viet shops, get a bunch of beer and go to the park/friend's backyard. Lately the boil shops have been taken over my the Vietnamese, so you might want to hunt down an authentic y'at boil shop for the real thing. I don't much care for the most of the fine dining I've had in nola - a bit overrated. Cochon is cool. Irene's is great and fun. August is supposed to be the best in town currently; I haven't tried it yet (found Luke to be pretty poor). I really want to try Gautreaux's, but never have (it's number one on my to try list for my next visit). Galatoire's is always fun.