Modern nutrition has become too obsessed with fat and muscle, and has been ignoring nutrients and vitamins. Your nutritional needs do not begin and end with your biceps or quads. They also include your skin, your teeth, your bones, your internal organs and endocrine system, and especially your brain. An all-Twinkie diet at a net calorie deficit will cause you to lose weight, but it won't provide adequate nutrition (again, I am using "nutrition" in the holistic sense of the word, and not just in the caloric or macronutrient sense). Vitamin defficiencies are moderately to extremely hazardous to your internal health, as are vitamin overloads of certain types. A multivitamin is a decent way to supplement a vitamin-defficient diet, but it is a poor substitute for food-derived vitamins.
I'd love to see a more longitudinal, i.e., years-long, study about this Twinkie diet and its effects on the professor's total systemic health over the long term. I bet he would not sign up for such a study.
