Havent they found that Ecstacy use burns out the receptors that accept the neurotransmitters that scoot across the synaptic gap (medical types might want to chime in here). I can see wanting to alter your brain chemistry temporarily. Some of the best times I have ever had were in an "altered" state. But from what I understand Ecstasy is suspected of leaving permanent damage. Have you ever run into some burnt out Haight/ashbury frybrain? You dont want to go there.