What is the most useful health advice you've ever got? - Page 5

Originally Posted by db_ggmm

Operaman vs slack tide?

Originally Posted by mm84321

Problems really don't appear until you start consuming over 50g a day, which is pretty easy on a western diet of processed foods, and pretty difficult when you are eating it in its natural state with its companion of fiber. links to evidence? Ethanol is an acute toxin, whereas fructose is a chronic one (the reason the FDA won't regulate it). again links to FDA saying fructose is a chronic toxin and that's why they won't regulate it? Heres the breakdown: Let's say for instance you consume 120 calories of ethanol (a shot of brandy). 12 of those calories will be consumed by the stomach and intestine in what is known as the first pass effect. Another 12 are used by the kidney, muscles, and brain. There goes 20%. The remaining 96 calories get directly dumped on the liver. First thing that happens upon entering the liver is the conversion to acetaldehyde<--(cross links proteins, which can cause cirrhosis; also generates reactive oxygen species which can go on to damage proteins in the liver). So the acetaldehyde goes on to acetate which enters the mitochondria participating in the TCA cycle generating energy (alcoholics need energy from something). Now, due to the relatively large load of 96 calories of ethanol being metabolized you are going to produce a lot of citrate, isn't citrate produced by basically anything entering the TCA cycle? why would ethanol acetate particularly form more citrate? acetate is acetate regardless of source all of which is going to be metabolized and shipped out of the liver in the form of VLDL (very low density lipoprotein: the real bad cholesterol) by SREBP-1. This is the dyslipidemia of alcoholism. Now let's assume you take in 120 calories of sucrose (half fructose, half glucose) as one glass of orange juice. Out of the 60 calories of glucose, 12 go to the liver and 48 goes to the rest of the body. Fructose: all 60 goes to the liver because only liver can metabolize fructose. So what is it called when you take in a compound that can only be metabolized by the liver? Poison. So fructose goes into the liver, gets metabolized by fructokinase, converts to fructose-1-p, in the process ATP gives up one phosphate to ADP. 72 calories have to be phosphor-elated (12 from glucose) which is three times the amount from just consuming 120 glucose calories alone (from a sweet potato, for instance) how is this 3 times more? legitly asking. You lose a lot of phosphate from this process. Scavenger enzymes in the liver are sent out to rescue the phosphate, which eventually leads to the waste product of uric acid, which can cause gout and hypertension but only in extremely high concentrations. most of its excreted through urine. Fructose will then get metabolized into pyruvate which enters the mitochondria just like with ethanol throwing off a lot of citrate. again pyruvate is what all energy sources enter the TCA cycle as. how is pyruvate from fructose different from glucose? The dihydroxyacetone-P and glyceraldehyde created by this metabolization can reform fructose-1,6-bis-P, which then reforms with glyceraldehyde to create xylulose-p-5 that stimulates pp2a which then activates the transcription factor carbohydrate response element binding protein, or ChREBP for short, which activates the three new fat making enzymes through a process known as de novo lipogenis. Fructose 1,6 biphosphate is part of glycolysis. Glucose and fructose both produce fructose 1,6 biphosphate. I'm not sure again why G16BP from fructose would be processed differently. Also ChREBP is also produced in response to high amounts of glucose. Then you still have all that citrate that the liver wants to ship out (just like with ethanol. So it too gets packaged with VLDL and shipped out. This is the dyslipedmia of obesity from fructose consumption. However, some fat wont make it out of the liver, just like with ethanol, why? how does it just stay in the liver? Fructose and ethanol are the same because they come form the same place. Both are sugars and have the same properties, however ethanol is fermented. Only difference. "Fructose is alcohol without the buzz." I dunno man. This seems pretty off. They're different compounds with different effects. Ethanol is definitely not a sugar

Originally Posted by Zekes

The best health advice that I heard for today was being told to me by my friend that I have to eat healthy and love my body.