5'10 180 lbs with 25" thighs from two decades of soccer and lacrosse. Correctly fitting jeans (pants in general) are a bitch to find. Usually have to go up at least a size and work from there. Slim fitting jeans were abandoned back in high school. Eventually when I have some spare cash, I'm just going to resort to bespoke pants in general, it's probably worth it in the end.
FWIW, AG jeans actually fit me pretty well, even with the 24" thighs. I can fit in a 31 waist for most cuts, 32 for the one-wash protoge. I definitely have to size up to around a 33 or higher in things like chip and pepper, true religion, deisel, etc.
*sigh* At 5'11" and 230 lb, I have 31" thighs, 49" hips and a 34" waist. This is due to a confluence of genetics and a proclivity toward full, olympic style squats...and before you ask, yes, I know how to use a tape measure. A lot of us wrestlers are built similarly. What I find is that a relaxed cut like a Levi's 550 fits like it was painted on. Forget about premium denim; their baggiest still doesn't have enough seat.
6'3" 180 with 24" thighs. I've been playing football/basketball since I was in elementary school till now. I am actually trying to get back down to 170 again and get the thighs down to around 22". I've had the same problems finding jeans, but once I tried on an APC new standard, I was sold!
It's funny buying a 31waist in one pair of jeans and a 33 in another....argh!