Pete Turner, the CEO of Cost Technology, has discovered that on average 30% of a companies customers deliver the majority of a companies profits.
He didn't really "discover" that. The Pareto Principle has been proven in many arenas.
All things being equal, a successful, established player would be incredibly stupid not to take all steps to protect their marketspace. These steps can, and do, include seeking regulation to aid the process.
I think AFran has a point in that a majority of businesses' lobbying dollars are spent lobbying against regulations.
I think he might be missing that a lot of dollars are spent shaping the regulations that are passed, especially in certain industries. U.S. Sugar, the single largest agricultural industry campaign donor is especially notorious for this (at least in Florida), and in a few decades will probably be the only political entity still lobbying for the Cuban Trade Embargo.