Auto? No, can't be deducted unless it's for business.
School? Depends on what you mean and your specific situation. Tuition and fees are usually deductible, but unless you own a house it is unlikely that you're going to be better off not taking the standard deduction. Most students end up taking either the Hope Credit or the Lifetime Learning Credit. Google these, read about them, etc. Honestly though, TurboTax does all of them for you, and you should really be using it.
Note: All of this is generalities and may not apply in any way to your individual situation. I am not an accountant, lawyer, financial planner, or even particularly bright. Consult the services of a real professional.