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Originally Posted by
asdf 
Stein et al (2006) found no significant change in protein turnover during 14 days of strict bed rest in human subjects. Synthesis and degredation were equally reduced.
That doesn't mean skeletal muscle isn't lost.
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I reiterate the weight/size you lose during short periods of lowered activity is merely destorage of glycogen and water that muscles uptake during intense training. This is the equal opposite of the weight gain you experience when you start working out, or re-start after periods of inactivity.
Insulin sensitivity varies, and a trained person will likely have little change in insulin sensitivity over a short period of time. If anything, short-term inactivity will result in size gains depending on diet and previous activity levels.