Just remember that it's not a sprint and you'll make progress you're happy with.
So what's progress here coming off of a 10 day vacation? The following is a real world example that MANY trainees can identify with.
John the bodybuilder started his first training cycle squatting 345 x 8. Twelve weeks later (remember there's one or two deloads somewhere in there) he's already at 385 x 8. Now he's really grinding them out, dragging ass, no motivation, going through the motions, or whatever else have you. Everything feels like it's a thousand pounds and everything is a max effort. Training has lost it's luster. Sick of measuring foods and he's looking for excuses not to train. Would another deload suffice? No, this time he's sick and tired of training and waking up in the mornings to go in. Well, to me that sounds like you're completely out of wood.
SO, he takes a 7 day total vacation. At the end of the week, he feels better, but still doesn't really feel like lifting. He says to himself, "Screw it" and extends it to 10 days because he wanted to take the family to Disneyland. By day 9 he's literally chomping at the bit to get back in there. Training starts to dominate his every thought for the first time since as far back as he can remember! Day 10 - Time to unleash the hounds! He wakes up before the alarm clock goes off and jumps in the car. Halfway to the gym he glances at the mirror and sees he's foaming at the mouth. His eyes are bugging out and he's white knuckling the steering wheel while listening to Slayer.
Keep in mind, John the Bodybuilder is VERY experienced and this is not his first rodeo. He wants to be smart about his loading and doesn't want to just go back in there balls to the wall. In doing so, it'll disappoint him (ruin motivation), increase DOMS to the point to where he walks like he got passed around the prison block, and probably shorten his loading phase by a month. He thinks, "To hell with that, I've waited ten days and I'm not about to screw myself over!"
So he takes the experienced approach and EASES himself back into it. Instead of starting off with a 385 x 8 squat which he may or may not be able to do, he drops it down to 355 and busts out a set of 10 reps. Very easy for him. In fact, he remembers his first training cycle when he put a lot more effort into the 345 x 8 according to his last journal's first workout. He thinks to himself, "I'm going to tear some shit up this cycle!"
14 weeks later (of course a few deloads worked in there IF/when he needs them), he wound up squatting 405 x 7! He looks back in his journal and sees he last ended with 385 x 8. Holy shit - A new PR! Now our hero is as happy as a pig in slop.
Over the years, our hero continues throwing more wood on the fire (deloads) when he feels like the fire's going out and progresses by leaps and bounds. Every so often (sometimes many months), he leaves to go get some more wood (time off). Without going to the gym he gets an extra two hours of sleep, more time to himself, and doesn't worry about planning and cooking meals. If he feels like going to the Cheesecake Factory, he orders whatever he damn well pleases, and tops it off with a few Sam Adams. Life's GOOD. By day 7, all the cravings and relaxation is out of his system and he's once again rededicated to training. See, our hero isn't worried about gaining 1% bodyfat back or losing 10 lbs off his deadlift. He knows it's only a week, and that it'll get fixed during his loading phase (which is 12 times longer than his simple week of relaxation).
Additionally, because he knows when to unleash hell and when to pull back on the reigns and his TOTAL CONSISTENCY over the MANY YEARS of loading and unloading has brought him up to a 500 x 10. While that's tremendous progress, he's still never really satisfied. His legs are thick as tree trunks, but all that matters to John that it's not about where you begin, it's always about where you END!