As JS said, the lines of the brogueing and their spacing from the welt which are what he outlined in the red boxes. The only way for that to really happen is that when the uppers were lasted, they weren't properly aligned on the last. It's not a huge deal, unless if becomes distracting to the eye. It doesn't affect longevity of the shoe. The ones that the OP showed are acceptable for seconds, but definitely not for firsts, in my opinion.