For me, it's not seeing the ads that's the problem, it's the unscrupulous forces that drive them, the way they collect you, profile you, store you, and sell you. Often hidden, and with no oversight. Not to mention the risk they pose to your digital property should you happen to click on the wrong ad (or, more likely, when it decides to click on itself for you).
I don't know why seeing ads is being presented as the problem. It's not. If that were the case -- if it were a just minor, temporary annoyance, rather than a genuine risk -- I would gladly disable the following:
But for right now, I can click on any one thing that Ghostery blocks and read, in detail, of the massive corporate interests behind it, and the shitstorms of abuse they love to inflict, without anyone's knowledge or consent.
But yeah...big coat hangers are also annoying.