Museum like selecting a finer and thinner super 150 cloth for your bespoke suit,
compared to a more durable super 100 cloth.
Well, in what context? If you are thinking of a dress shoe, I can't imagine there would be a meaningful difference in how the shoes perform or endure - assuming proper care for both. If you are thinking of a rugged lugged-sole hiking boot, then perhaps.
That's correct, for dress shoes not much difference at all. However, from a craftsman point of view, then yes.
They will have to be a touch more careful with the delicate leather during the stretching and lasting process.