Probably depends on the weave (and less on the thread count). I am a big fan of the 200 tc shirts but would be very interested in hearing more about 300 shirts. The salesmen at Madison ave describe the 300's as a bit delicate. My concern is durability. So if anyone has put these through 30+ wears please chime in.I have (7) 200 tc shirts and all have been worn 2-3 times. Going to take a while for me to report back on durability.