The 1220 is slimmer than the Base S, and more structured. If you want an Isaia comparison, look to the Base V. As for the Zegna Milano, the 1220 compares favorably in terms of fit, though the shoulders might be a bit wider.
Yes, this year has really been a change for Tom Ford. A lot of what is in the store is still the classic stuff, though the fit has changed some. The suits have gotten fuller, the peak lapel has switched to notch with a lower gorge, and the overall silhouette has changed a bit.