I'm sure someone has done it, but I'm not sure why. Presas are mostly shit. Neos more so. The idea that someone had access to two dogs from those breeds worth putting together is highly unlikely. Besides, if you had a great Neo you'd be better off making better little Neos.
Certain breeds don't mix well - Rotts for example - and the Presa may be in that category.
That cover looks like an old EC cover. I haven't read an Archie comic in a lot of years (think I'll pick up this one) and was shocked to see my 10-year-old nephew reading one. Still resonates. And would hit Midge. lefty