(Oh, are we only doing major cities?)
New York, New York / Tristate (seriously, most of the surrounding "towns" are bigger than some of the cities lower on this list)
Harrisburg, PA - Eh, I guess. Not that major though....(and not where my best thrifting is either)
Baltimore MD, may be a better choice...about equidistant. (and still not where my best thrifting is)
Wichita, Kansas -- population 350,000 nearest major City either Kansas City or Oklahoma...