Was able to pick mine up today. The bigger screen is nice but one handed use is challenging and I have big hands. My thumb can't reach the top corners unless I shift the phone a bit but then it feels like the round edges would make it pretty easy to slip out.
Sidenote: I've noticed my 5S running slower ever since updating to ios8. Wonder if there's any truth to those articles a while back saying Apple intentionally slows down older models when releasing new software.