It seems that all the studies that show glucosamine helps are from Europe. Other studies including the NIH's GAIT study were generally negative. There's also exceptionally high placebo response rates in the studies. I don't know of any good study that shows it affects the natural history of osteoarthritis. But since it's generally safe, if you think it works, then go ahead and use it.
2/1/10 at 11:09pm