Wear them- people wear nantucket reds all the time and they look great. It'd be nice to see someone in pants a color other than black, blue, or khaki.
Sorry I don't know what to wear with them though- not too good with colors.
Also, they had a great line of jeans called Stitch, but for 300 dollars a pair I decided to pass.
Here they are for around 260- maybe there's a coupon floating around that can make it alittle less...